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This Is Your Brain on Drugs

According to a recent study by University of Pensylvannia scientists, there were small or limited associations between [adolescent] cannabis use and structural brain measures. But even calling the effect small is aggrandizing harms. Their data didn’t support the notion that teens using cannabis causes any changes in the developing brain.

Injecting Uncertainty into Science

A rat smoking weed

Preclinical studies are supposed to provide precise, controllable, and translational models for human diseases. But the manipulations that researchers use — like injecting a precise dose of THC into a rat — may sometimes miss important points. What if smoking and injection have different effects? How might this bias results? University of Florida researchers asked just that question, studying the effects of injected vs. smoked THC in rats. Injecting low doses of THC impaired memory.

Low Dose THC Can Improve Cognition

Improved brain function

THC and other cannabinoids are known to induce neurogenesis — the creation of new neurons — in the brain. There are reasons to believe that this can positively influence diseases like dementia or traumatic brain injury, as well as the ability to learn. Malaysian researchers recently probed the question, does THC improve cognition by inducing neurogenesis? Yes, but only at the right dose.

Cannabis and ADHD

Abstract illustration of a person viewing into a mind

A study in Molecular Psychiatry with tens of thousands of people found an association between ADHD and cannabis use. Their data suggests that ADHD causes later cannabis use, which may support the notion that THC is used to self medicate (although ADHD is associated with heavier use of many drugs).

Project CBD Releases Educational Primer on Cannabinoid-Drug Interactions

Given the increasing acceptance and prevalence of cannabis as a therapeutic option, it’s important for physicians and patients to understand how various cannabis components interact with commonly consumed pharmaceuticals. This report details potential interactions between CBD and common treatments for a number of conditions.