Candidates for organ transplant are thoroughly screened, and illicit substance use is usually disqualifying. But cannabis is well established as a medicine (as it has been for millennia) and should not prevent patients from receiving a necessary transplant. Doctors at a pediatric hospital in Delaware recently described the thought process around allowing or prohibiting cannabis use.
Organophosphates are a class of insecticides like chlorpyrifos and soman. Sarin, used as a chemical weapon, is also an organophosphate. Many of these are neurotoxic, owing to their ability to amplify the neurotransmitter acetylcholine, which paralyzes insects and causes their death. A recent study from medical researchers in Maryland and Pennsylvania described the human toxicity in detail and explained why cannabinoids may be protective for humans.
A major benefit of legalization is regulation (at least in theory). Cannabis in a legal market can be held to safety standards such as the absence of dangerous pesticides. While autonomous community-enforced regulation can exist without government intervention, this does not happen at the global scale which the cannabis industry has reached today. So how well are governments doing with their pesticides regulations?
In 2017, Michigan’s government founded a commission to recommend policy on cannabis and driving, specifically how to set THC limits. Two years later, in March 2019, they released their conclusion:
[T]he Commission finds there is no scientifically supported threshold of ∆9-THC bodily content that would be indicative of impaired driving (emphasis added).
According to a recent study by University of Pensylvannia scientists, there were
small or limited associations between [adolescent] cannabis use and structural brain measures. But even calling the effect small is aggrandizing harms. Their data didn’t support the notion that teens using cannabis causes any changes in the developing brain.