Pharmaceuticals

Cannabis Legalization and Opioid Overdose

Oxycodone pills on a blue background.

Opioids leave much to be desired in medical treatment. They are highly addictive, very lethal, and not all that effective for treating chronic pain. Cannabis, particularly THC, is promising for its opiate-sparing properties: preclinical work indicates that cannabis synergizes with the painkilling effects of opioids and reduces the development of tolerance (perhaps because of this synergy) but does not increase opioid-induced respiratory depression which leads to death. Moreover, states that legalize cannabis see a decrease in opioid prescriptions.

Dosing Pure CBD

CBD is clearly a useful medicine in the treatment of some types of epilepsy, yet patients are faced with dilemmas when they must decide which product to use, how to incorporate it with other medications, and how to begin dosing.