Obesity

Real-World CBD Evidence, CBD and Ketamine, and More . . .

New developments in the burgeoning field of cannabinoid research.

CB1, Gene Expression & Obesity

Abstract DNA strand

A synthetic cannabinoid pharmaceutical called Rimonabant was briefly approved in Europe as an anti-obesity drug. Rimonabant inhibits the CB1 receptor, reducing its activity below normal levels and blocking other compounds, like THC or anandamide, from activating it. It was taken off the market in 2008 for causing suicidal thoughts, among other psychiatric problems, which occurred when this pharmaceutical shut down cannabinoid activity in parts of the brain.

Big Bellies: Pregnancy & Obesity

Man and pregnant woman comparing belly size

A mother’s diet while she’s pregnant is known to affect the child’s eventual food preferences. A new animal study from scientists in the U.S. and Brazil examines how a high-fat diet during pregnancy influences the offspring’s predisposition to obesity and related complications later in life, and this appears to be mediated by changes in the endocannabinoid system.

ICRS 2018: Report from Leiden (Part 2)

During the first week of July 2018, five-hundred-and-thirty-five delegates from five continents met at the University of Leiden in the Netherlands for the 28th annual symposium of the International Cannabinoid Research Society (ICRS). The four-day conference showcased recent scientific discoveries about cannabis components and various ways of targeting the endocannabinoid system to improve health outcomes.

Obesity

Obesity is a condition that is associated with an excess amount of body fat, in particular a Body Mass Index (BMI) of 30 or greater. Often there are genetic and environmental at play. Obesity is associated with chronic inflammation, diabetes, and many other metabolic conditions.

Cannabis Conversations

Louis Armstrong, the legendary jazz artist and lifelong cannabis smoker, returns to his ancestral homeland
Expert cannabis botanist and geneticist Ryan Lee talks to Project CBD about breeding cannabis, THC & CBD content, and how to interpret lab data.
Project CBD speaks with Dr. Rachel Knox about "endocannabinology," THC/CBD synergies, and whole food nutrition.

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