New scientific data shows that CBD interacts directly with the CB1 cannabinoid receptor in ways that are therapeutically relevant while modulating the psychoactive effects of THC. CBD lowers the ceiling on the ability of THC and endogenous cannabinoids to stimulate CB1. Cannabidiol is a profound mood-altering substance, even if it may not have a “high”.
An important study from the Journal of Neuroscience shows that marijuana use does not cause structural brain changes.
In response to urgent need expressed by parents of children with intractable epilepsy, the U.S. Food and Drug Administration is allowing Investigational New Drug studies of purified CBD (cannabidiol) as an anti-seizure medication.