Cannabis Science

Book Award for Smoke Signals

Smoke Signals wins James A. Duke Excellence in Botanical Literature Award

The nonprofit American Botanical Council (ABC) is pleased to announce this year’s James A. Duke Excellence in Botanical Literature Award recipients. The recipient in the popular and consumer books category is Smoke Signals: A Social History of Marijuana—Medical, Recreational, and Scientific by Martin A. Lee.

CBD: Safe at High Doses

CBD safe at high doses

Oral administration of CBD is safe and well tolerated in humans, according to clinical trial data published by the journal Current Pharmaceutical Design. Investigators at Kings College in London assessed the physiological and behavioral effects of CBD and THC versus placebo in a randomized, double-blind, crossover trial.

Taming THC

Cannabis Terpenes
THC has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of CBD and terpenes to cannabis pharmacology and analgesia have been scientifically demonstrated.

Tale of Two Cannabinoids

THC and CBD synergy

This study examines the current knowledge of physiological and clinical effects of THC and CBD and presents a rationale for their combination in pharmaceutical preparations. Cannabinoid and vanilloid receptor effects as well as non-receptor mechanisms are also explored.