Autoimmune Diseases

Graft versus Host Disease (GvHD)

An illustration of doctors hands holding out different organs. There are lungs, kidneys, intestine, liver, brain, and heart.

Graft Versus Host Disease (GvHD) occurs when the white blood cells in a transplanted organ or bone marrow begin to attack other cells in the recipient’s body. It also occurs, rarely, after some blood transfusions where the blood is not first irradiated. It results in inflammation in various organs, and can increase chances for systemic infection - a dangerous complication.

Scleroderma

An illustration of a woman with some common symptoms of scleroderma. There are two images pulled out to illustrate specific symptoms. The image of a stomach filled with yellow fluid represents esophageal dysfunction. An illustration of a hand represents the occurance of ulcers, calcinosis, sclerodactyly, Raynaud's phenomenon, and telangiectasias.

Scleroderma is an autoimmune disease characterized by the overproduction of collegen and other fibrotic cells. This overproduction generally first appears on the skin, although it can also express systemically.

Lupus and ABHD6

Systemic lupus erythomatosus, often simply called lupus, is a severe autoimmune disorder where the immune system attacks the nucleus of cells — their genetic control center. Problems can be expressed anywhere in the body, though rashes in the skin, joints, and vital organs are most common. Treatment of lupus generally requires intense immunosuppresive drugs, often targeting inflammatory molecules called interferons. But these drugs make a person more susceptible to other diseases.