Autoimmune Diseases

Cannabinoids for Scleroderma

Clinical trials are underway to treat a rare autoimmune disease by targeting the endocannabinoid system.

Cannabinoids for Scleroderma

Two compounds that target the endocannabinoid system are currently in development to treat scleroderma – and they’re already in clinical trials. Pharmaceutical researchers have their sights set on developing a drug that bypasses CB1 while boosting CB2. Referred to as a “selective CB2 agonist,” such a compound would appear to have potential as a treatment for scleroderma.

Immune Function

man coughing
Autoimmune diseases are diseases in which your body’s defense system triggers an abnormal inflammatory response. MS, Crohn’s, lupus, scleroderma, and graft vs. host disease are autoimmune diseases.

Lupus & ABHD6

Hand holding purple ribbon

Systemic lupus erythomatosus, often simply called lupus, is a severe autoimmune disorder where the immune system attacks the nucleus of cells — their genetic control center. Problems can be expressed anywhere in the body, though rashes in the skin, joints, and vital organs are most common. Treatment of lupus generally requires intense immunosuppresive drugs, often targeting inflammatory molecules called interferons. But these drugs make a person more susceptible to other diseases.

Inflammation

woman rubbing wrist
Inflammation is the process by which your body protects you from infection but unregulated becomes a disease. Symptoms include redness, swelling, pain, and stiffness. Chronic inflammation has been linked to diseases like heart disease or stroke, and may also lead to autoimmune disorders.

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