Anxiety & Stress

Anandamide Modulates Panic

New research from Brazil examines how endocannabinoids, specifically anandamide, plays a role in panic-like reactions in mice.

Anandamide Modulates Panic

Rainbow Boa Snake

Panic, as a mental health disorder, results from overactive stress hormones, hypersensitivity to certain neurotransmitters, and a desensitization to the parasympathetic system — which is supposed to quell the fight-or-flight reaction after a threat has disappeared. New research from Brazilian scientsts in São Paulo examined how endocannabinoids, specifically anandamide, plays a role in panic-like reactions in mice. Injecting various doses of anandamide into a brain region called the dorsomedial hypothalamus, they found that moderate doses suppress panic, but high doses have no effect.

Results Pending

Spider in web

Scientists from the Netherlands recently published the protocol for an upcoming study examining how CBD might be helpful in treating specific phobias. The endocannabinoid system is required for eliminating fearful memories, or at least making them palatable. But why have they only published their methods? It’s part of an ongoing movement to make science more accurate. Many statistical methods assume that the researchers plan all of their data analysis before looking at any of the data.

Concussions & Alcoholism

distraught man with booze bottles

Traumatic brain injury (TBI) leads to numerous problems, including alcoholism and suicide. New findings indicate that endocannabinoids aid TBI recovery: When researchers boosted 2-AG levels shortly after injury, rats displayed less anxiety and less interest in alcohol. This is significant since alcoholism is a serious comorbidity of brain injury.

Depression & Cannabis

Depressed asian woman

Our moods are affected by our environment, life situations, genetics, and brain activity. Some individuals are simply happier than others, and research on CB1 (cannabinoid) receptor genes gives us some clues to why that happens. [1] However, even though some are seemingly genetically destined to find and maintain happiness easier, other variables in life cannot be minimized.

Cannabis & Sleep Disturbances

An African American man stands hugging a pillow with one hand to his face. He is wearing a bright yellow shirt and standing in front of a blue background. There are feathers on his shoulder and head. He looks frustrated and tired.
Quality sleep is critical to human emotional, mental and physical health, yet it eludes between 50-70 million Americans. Nishi Whitely explores why sleep matters, the role of the endocannabinoid system in sleep, and how cannabis and its components — in particular, CBD and THC — may benefit those with sleep issues.

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News & Reports

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Top Conditions

In compiling a list of conditions that CBD may help, we examined hundreds of peer-reviewed articles in scientific journals.

Cannabis Conversations

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