Published in full in Time magazine.
A compound found in marijuana can treat schizophrenia as effectively as antipsychotic medications, with far fewer side effects, according to a preliminary clinical trial.
Researchers led by Markus Leweke of the University of Cologne in Germany studied 39 people with schizophrenia who were hospitalized for a psychotic episode. Nineteen patients were treated with amisulpride, an antipsychotic medication that is not approved in the U.S., but is comparable to other medications that are.
The rest of the patients were given cannabidiol (CBD), a substance found in marijuana that is thought to be responsible for some of its mellowing or anxiety-reducing effects. Unlike the main ingredient in marijuana, THC, which can produce psychotic reactions and may worsen schizophrenia, CBD has antipsychotic effects, according to previous research in both animals and humans.
Neither the patients nor the scientists knew who was getting which drug. At the end of the four-week trial, both groups showed significant clinical improvement in their schizophrenic symptoms, and there was no difference between those getting CBD or amisulpride.Read full article
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Danish researchers have found that cannabis users with schizophrenia experienced significantly fewer gut-related issues than those of non-cannabis users.
After over a century of failing to find a causal link between cannabis use and schizophrenia, proponents of Reefer Madness have had to couch their warnings.
Schizophrenia is a chronic brain disorder. When active, symptoms can include delusions, hallucinations, trouble with thinking and concentration, and lack of motivation.
People have been studying the link between cannabis and schizophrenia for over a century. Research has not established strong evidence that cannabis causes schizophrenia, although there is an association. A new paper highlights some limitations of these studies.
A new study from researchers at Yale University suggests that an antipsychotic called haloperidol decreases the psychoactive effects of THC. Reading between the lines in research, it’s always important to check the dose administered. These scientists gave participants an i.v. injection of THC (0.0286 mg THC per kg bodyweight, to be exact). For an average adult in the U.S. that means injecting about 2 mg of THC.