Recipe for CBD & Mānuka Antibiotic Salve

Recipe for CBD & Mānuka Antibiotic Salve

CBD and Mānuka honey are potent allies in the fight against bacterial infections.
CBD and Mānuka honey are potent allies in the fight against bacterial infections.
Photograph of a honey dipper dripping honey into a ceramic bowl. Manuka flowers are laid over the  bowl.

CBD and Mānuka honey are potent allies in the fight against bacterial infections, including antibiotic-resistant Staph (MRSA). This potent healing salve combines two superstar ingredients shown to help heal minor wounds and stave off infection.


  • Kitchen scale
  • Spice/coffee grinder
  • Measuring cups and spoons
  • Spatula
  • Double boiler and/or crockpot
  • Fine mesh strainer or cheesecloth
  • Small glass jars for finished oil and topicals, preferably amber or other dark color


  • 1/2 cup CBD topical base oil
  • 1 tablespoon shea butter
  • 1 tablespoon Mānuka honey
  • 2-3 tablespoons beeswax pellets, or finely chopped beeswax
  • 1 teaspoon witch hazel
  • 6 drops tea tree oil
  • 6 drops lavender oil
  • 6 drops thyme oil
  • 6 drops oregano oil


  1. Make CBD topical base oil
  2. Warm CBD topical base oil in a double boiler.
  3. Add shea butter and beeswax and stir until fully mixed.
  4. Remove from heat and let cool to lukewarm.
  5. Add Mānuka honey and essential oils and stir until thoroughly mixed.
  6. Pour into small glass jars, label, date and store in a cool, dark place.


Due to the honey, this salve is a bit sticky, but it works extremely well. Apply a thin layer of salve over a clean, superficial wound or other area where antimicrobial action is desired. Not intended for deep or puncture wounds.

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Melinda Misuraca is a Project CBD contributing writer with a past life as an old-school cannabis farmer specializing in CBD-rich cultivars. Her articles have appeared in High Times, Alternet, and several other publications.

Copyright, Project CBD. May not be reprinted without permission.

Revision date: 
Feb 26, 2020

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