The history of marijuana in America has long been a history of competing narratives, dueling interpretations. What follows are 13 slides of key moments in the history of marijuana in the United States.
Oral administration of CBD is safe and well tolerated in humans, according to clinical trial data published by the journal Current Pharmaceutical Design. Investigators at Kings College in London assessed the physiological and behavioral effects of CBD and THC versus placebo in a randomized, double-blind, crossover trial.
Cathy Jordan first noticed something was wrong in summer of 1985 when she couldn’t pick things up. Her muscles weren’t responding. In 1986, she was diagnosed with ALS , also known as Lou Gehrig's disease. Nearly 20 years later she is still alive thanks to cannabis, her medicine of choice and necessity.
In a test of short-term memory skills, only users of "skunk"-type marijuana strains exhibited impaired recall when intoxicated, whereas people who smoked hashish or herbal cannabis blends performed equally well whether stoned or sober.
THC has been the primary focus of cannabis research since 1964, when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic contributions of CBD and terpenes to cannabis pharmacology and analgesia have been scientifically demonstrated.
This study examines the current knowledge of physiological and clinical effects of THC and CBD and presents a rationale for their combination in pharmaceutical preparations. Cannabinoid and vanilloid receptor effects as well as non-receptor mechanisms are also explored.
The misnamed Smart Approaches to Marijuana (SAM) recently produced a “fact sheet” entitled, Everything You Need to Know About CBD, that seeks to justify the continued prohibition of cannabis by misinforming the public about cannabidiol and THC.