Quick Hits

Welcome to Project CBD Quick Hits, where we collect some of the most interesting and informative tidbits of research into cannabis over the past week.
Posted: September 12, 2019
Cups of coffee with marijuana and roasted beans on a table
Some research has shown that caffeine can amplify the short-term forgetfulness caused by THC. A new study indicates that the caffeine may block other effect of cannabinoids. Read more
Posted: September 12, 2019
Marijuana leaves and a cup of coffee on white
It is increasingly recognized that cannabidiol can moderate many of the effects of THC, but the mechanisms by which CBD does this aren’t obvious. The neurotransmitter adenosine may be one important link. Read more
Posted: September 11, 2019
Close up pouring purified fresh drink water from the bottle on table in living room
Dosing CBD and other cannabinoids is challenging. An article in Molecules detailed the absorption and kinetics of a new formulation of self-emulsifying CBDRead more
Posted: September 10, 2019
Portrait of tender gentle romantic sweet lovely open-hearted african man showing big red heart in hands isolated on gray background
Researchers from eight different countries recently collaborated on an article warning about the dangers of teens falling in love. Read more
Posted: September 9, 2019
Close up portrait of beautiful young black woman smiling outdoors
The protective effect of cannabinoids for those living with Type 2 diabetes and obesity is particularly pronounced among people with schizophrenia. Why? Read more

More quick hits

Posted: 3 months 2 weeks ago

Researchers have modulated cannabinoid CB1 receptors in addiction treatment in order to affect cravings, the formation of habits, one’s sensitivity to triggers, withdrawal symptoms, and the pleasure one derives from drug use. Now scientists at the National Institute on Alcohol Abuse and Alcoholism have added a new factor to the list: feeling satiated.

Posted: 3 months 2 weeks ago

Cannabinoids have been proposed for numerous neurodegenerative disorders. As a matter of fact, scientists employed by the US government filed a patent in 2001 for Cannabinoids as antioxidants and neuroprotectants, citing their potential for treating Alzheimer’s disease among others.

Posted: 3 months 2 weeks ago

Driving under the influence of cannabis (DUIC) is framed as a major risk associated with legalizing cannabis. Studies on cannabis and driving suggest that lighting up before getting behind the wheel increases crash risk between 25-40%.

Posted: 3 months 2 weeks ago

The development of legal cannabis is associated with lower teen use and higher adult use. But many scientists, hesitant to give up a lifetime of prohibition, spin their data to emphasize danger.

Posted: 3 months 2 weeks ago

There has been a spate of recent articles on exercise and cannabis. Part of the runner’s high is attributable to endocannabinoid release. In Colorado, cannabis users are more physically active, on average.

Posted: 3 months 3 weeks ago
Police officer writing a ticket.
The push to criminalize cannabis has always revolved around race. As legalization movements gain momentum, it is important to pay back a debt owed to those who were most harmed by the drug war.
Posted: 3 months 3 weeks ago
 A cannabis branch and a syringe on a pink background
Researchers led by Yasmin Hurd at Mount Sinai recently showed that acute ingestion of high doses of pure CBD (400-800 mg) dramatically reduced participants’ response to heroin triggers while simultaneously ameliorating anxiety.
Posted: 3 months 3 weeks ago
Human liver anatomy with DNA structure, 3D render.
When the gene encoding FABP1 is deleted from rats, the rate of THC metabolism is dramatically slowed.
Posted: 3 months 3 weeks ago
Assorted pharmaceutical medicine pills, tablets and capsules and bottle on blue background.
Many drugs have been proposed as “treatment” for cannabis addiction, from pure THC or CBD-rich cannabis, to Ambien. These studies often employ participants who are not trying to quit, and overlook the harms associated with the replacement medication.
Posted: 3 months 3 weeks ago
ULcerative colitis. Frustrated man hugging his belly and keeping eyes closed. Disturbed male having pain in stomach.
CBD has shown promise in a number of gastrointestinal disorders, particularly autoimmune problems like Crohn’s. But a recent clinical trial of CBD may put a damper on hopes for treating ulcerative colitis.
Posted: 4 months 1 day ago
Oxycodone pills on a blue background.

Opioids leave much to be desired in medical treatment. They are highly addictive, very lethal, and not all that effective for treating chronic pain.

Posted: 4 months 1 day ago
A darkened hand holds a bag of synthetic cannabis

Synthetic cannabinoids (sCBs) are a class of designer drugs meant to interact with the endocannabinoid system.

Posted: 4 months 1 day ago
Conceptual image of liver damage as a result of drugs, viruses, toxins, bacteria, parasites, 3D illustration - Illustration
Posted: 4 months 1 day ago
Stethoscope on note book with Menopause words as medical concept

Hormone replacement therapy is used to reduce some of the symptoms of menopause. Although it can reduce problems like osteoporosis, hot flashes and depression, hormonal treatments come with risks including an increased likelihood of stroke and heart attack. Among those who use hormone therapy, scientists tend to believe there is a “critical window” where hormone replacement can reduce depression and the worsening memory associated with menopause. A new study from researchers in Xi’an, China, indicates that activating CB1 may prolong this window.

Posted: 4 months 1 day ago
Joyful mature man holding a joint and looking at the camera isolated on white background

The elderly are the fastest growing population of cannabis users. But how do hospice workers feel about their patients using cannabis? A recent survey by pharmacists at the University of Maryland asked palliative care practitioners about their opinions on cannabis use among hospice patients. Over 90% of workers support the use of cannabis, but most physicians did not recommend cannabis to their patients.

Posted: 4 months 1 week ago

Robert Randall was the first U.S. citizen to legally access cannabis based on medical necessity since the start of prohibition.

Posted: 4 months 1 week ago

Phytocannabinoids consistently confuse scientists because of the multiplicity of their actions. CBD, for example, binds to a handful of neurotransmitter receptors, as well as hormone receptors, ion channels, and a variety of enzymes. Receptors without a known endogenous ligand are called “orphan” receptors.

Posted: 4 months 1 week ago
CBD and anandamide

It has been known for some time that CBD acutely increases anandamide levels. The enhancement of

Posted: 4 months 1 week ago

If THC makes people forgetful while they’re high, one might reasonably expect that blocking the CB1 receptor that mediates the high will promote focus and the ability to learn. But is this true?

Posted: 4 months 1 week ago

It’s increasingly recognized that the runner’s high, which used to be attributed to endorphins, is conferred partly by endocannabinoids in the brain. In response to the stress of exercise, the brain produces anandamide, “the bliss chemical” which provides that feeling of elation along with pain reduction and health benefits.