Combining CBD with Cancer Treatment

Combining CBD with Cancer Treatment

A review of 10 studies that shed light on how CBD might interact with cancer treatments.
cancer cell and lab tray with dropper

Scientists in at Western New England University in Springfield, Massachusetts, briefly review 10 studies that shed light on how CBD might interact with cancer treatments. Half of these studies examine how CBD can affect the metabolism and distribution of anticancer drugs, a topic Project CBD has been discussing for years. As the authors describe, large doses or regular use of CBD can both increase and decrease the levels of different drug-metabolizing enzymes called CYPs, which will alter the effectiveness of a pharmaceutical. At even higher doses, CBD can also modify the expression of certain proteins produced by cancers to resist chemo. In mice, CBD prevents or reduces neuropathy caused by the chemotherapy paclitaxel. (The condition where even mild stimulus causes pain is called allodynia.) The New England scientists also highlight a few papers in which CBD synergizes with chemotherapy, improving the survival from glioblastoma (a severe brain cancer) and multiple myeloma (a type of bone cancer). These interactions make clear that CBD can influence cancer treatment, but they don’t shed much light on how many people might be helped (or hurt), and how to identify those groups of people. Yet THC is already approved for treating wasting syndrome in cancer patients. Despite the schedule 1 status of cannabis, it behooves the medical community to set up trials that take advantage of the already-existent group of people using cannabis while treating cancer. There are some legitimate concerns and many compelling possibilities.

Find CBD near you

Browse hundreds of retail locations for quality CBD products.

Search

News & Reports

An excerpt from Cannabis is Medicine by Dr. Bonni Goldstein

Top Conditions

In compiling a list of conditions that CBD may help, we examined hundreds of peer-reviewed articles in scientific journals.

Cannabis Conversations

Project CBD talks with Dr. Bonni Goldstein about whole plant cannabis remedies, nonintoxicating cannabinoids, and cancer care for children.
Expert cannabis botanist and geneticist Ryan Lee talks to Project CBD about breeding cannabis, THC & CBD content, and how to interpret lab data.
Project CBD speaks with Dr. Rachel Knox about "endocannabinology," THC/CBD synergies, and whole food nutrition.

Top Stories