Caryophyllene Reduces Alcohol Consumption

By Adrian Devitt-Lee On July 16, 2019
Caryophyllene and leafy greens

Terpenoids — the volatile compounds that give many plants their smell — appear to confer some of the medical effects of cannabis. Caryophyllene (BCP) and its derivative caryophyllene oxide (BCPO) are particularly significant terpenoids found in many green leafy vegetables. They activate the CB2 receptor, which, according to a recent study, prevents some of the harmful effects of drinking alcohol. The researchers gave varying dietary concentrations of BCP and BCPO to mice consuming alcohol. A high dose of BCP reduced some effects of alcohol. A much lower dose of BCPO reduced both the amount of alcohol the mice would drink as well as some of the addictive and behavioral effects of alcohol.

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Adrian Devitt-Lee, Project CBD's chief science writer, is employed as a research chemist by the University College of London.