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Catch up on the latest developments in cannabis science, medicine, culture, and politics.

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Preventing Pain with Orphan Receptors

Mexican and Texan scientists describe the modern approach to pain treatment and propose a future role of cannabinoids, GPR18, and GPR55 in preventing pain
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Natural High: CBD Augments Anandamide

It has been known for some time that CBD acutely increases endogenous cannabinoid levels.
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CB1 & Learning

If THC makes people forgetful while they're high, one might expect that blocking the CB1 receptor will promote focus and the ability to learn. It doesn't.
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Exercise for Depression

Endocannabinoid levels are often diminished in people with depression, and restoring cannabinoid tone with exercise seems promising.
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Cannabis & the Immune System: A Complex Balancing Act

A new wave of research points toward cannabinoids having an adaptive, immunomodulating effect.
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CBD & Organ Transplant

Very high doses of CBD might interact with immunosuppressive drug used in transplant patients
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Dosing Pure CBD

CBD is clearly a useful medicine in the treatment of some types of epilepsy, yet patients are faced with dilemmas when they must decide which product to use.

THC Makes Oxycodone Safer

Many prohibitionist arguments are being flipped on their heads.
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Placebo Genetics

The placebo effect accounts for roughly half of the efficacy of opioids and antidepressants.
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Into the Weeds

The EPA has refused to offer guidance for pesticides on cannabis.

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News & Reports

25 years of groundbreaking research — an annotated history.

Top Conditions

In compiling a list of conditions that CBD may help, we examined hundreds of peer-reviewed articles in scientific journals.

Cannabis Conversations

Project CBD talks with Dr. Bonni Goldstein about whole plant cannabis remedies, nonintoxicating cannabinoids, and cancer care for children.
Expert cannabis botanist and geneticist Ryan Lee talks to Project CBD about breeding cannabis, THC & CBD content, and how to interpret lab data.
Project CBD speaks with Dr. Rachel Knox about "endocannabinology," THC/CBD synergies, and whole food nutrition.

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