アルツハイマー病
アルツハイマー病・認知症
アルツハイマー病は、記憶の喪失、精神錯乱、意思伝達の障害などが特徴の、進行性の知的機能の低下です。
アメリカ政府が雇用した科学者らは、2001年、カンナビノイドに抗酸化物質および神経保護物質としての特許を取得し、アルツハイマー病その他の疾病の治療に有益である可能性を述べています。
ちょっと解説
参照論文：CBDと アルツハイマー病
- Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
- The therapeutic potential of the endocannabinoid system for Alzheimer’s disease
- Endocannabinoid signalling in Alzheimer’s disease
- A molecular link between the active component of marijuana and Alzheimer’s disease pathology
- Neuroprotective effect of CBD… on beta-amyloid-induced toxicity in PC12 cells
- The Potential Therapeutic Effects of THC on Alzheimer’s Disease
- The Role of Endocannabinoid Signaling in the Molecular Mechanisms of Neurodegeneration in Alzheimer’s Disease
- Cannabinoids for the treatment of dementia
- CBD in vivo blunts beta-amyloid induced neuroinflammation by suppressing IL-1beta and iNOS expression
- CBD: A promising drug for neurodegenerative disorders?
- Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer’s disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition
- The role of the endocannabinoid system in Alzheimer’s disease
- The role of phytochemicals in the treatment and prevention of dementia
- Cannabinoids for the treatment of dementia
- Cannabidiol Promotes Amyloid Precursor Protein Ubiquitination and Reduction of Beta Amyloid Expression in SHSY5YAPP+ Cells Through PPARγ Involvement
- Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
- Can Marijuana Prevent Alzheimer’s?
- Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia
- Natural Phytochemicals in the Treatment and Prevention of Dementia: An Overview
- Delineating the Efficacy of a Cannabis-Based Medicine at Advanced Stages of Dementia in a Murine Model
- CBD Modulates the Expression of Alzheimer’s Disease-Related Genes in Mesenchymal Stem Cells
- In vivo Evidence for Therapeutic Properties of CBD for Alzheimer's Disease
- Neurological aspects of medical use of CBD
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