Epilepsy & Seizures
In this excerpt from "Foundational Concepts in Neuroscience: A Brain-Mind Odyssey" neuroscientist David E. Presti discusses runaway excitation and its role in epilepsy.
Cannabinoids, particularly CBD, have taken the limelight with their dramatic life-saving effects in some cases of intractable epilepsy.
Australian scientists recently published an open label study of Epidiolex in pediatric epilepsy.
Warning about the dangers of drinking over 10 bottles of Epidiolex at once adds nothing useful to the discussion.
Very high doses of CBD might interact with immunosuppressive drug used in transplant patients
CBD is clearly a useful medicine in the treatment of some types of epilepsy, yet patients are faced with dilemmas when they must decide which product to use.
The study also provides support for using CBD as a first-line treatment for epilepsy, rather than a last resort.
How do CBD-rich cannabis oil extracts compare with CBD isolates?
Given the increasing prevalence of cannabis as a therapeutic, it’s important physicians and patients understand how cannabis interacts with commonly consumed pharmaceuticals.
High dose? Low dose? CBD? THC? Optimizing your medical use of cannabis may entail some experimentation.
Science abstracts on CBD and Epilepsy & Seizures
- CBD for children with Dravet’s and intractable seizures [VIDEO]
- Report of a parent survey of CBD-enriched cannabis use in pediatric treatment-resistant epilepsy
- Medicinal marijuana stops seizures, brings hope to a little girl
- Cannabinoids for epilepsy
- Cannabis, CBD, and epilepsy – From receptors to clinical response
- The non-psychotropic plant cannabinoids, cannabidivarin (CBDV) and cannabidiol (CBD), activate and desensitize transient receptor potential vanilloid 1 (TRPV1) channels in vitro: potential for the treatment of neuronal hyperexcitability
- Chronic administration of CBD to healthy volunteers and epileptic patients
- Endocannabinoid system protects against cryptogenic seizures
- Seizing an opportunity for the endocannabinoid system
- Cannabidiol: promise and pitfalls
- Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
- Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy
- Cannabidivarin (CBDV) suppresses pentylenetetrazole (PTZ)-induced increases in epilepsy-related gene expression
- CBD exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
- Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
- Hypnotic and antiepileptic effects of CBD
- The cannabinoids as potential antiepileptics
- Cannabidiol–antiepileptic drug comparisons and interactions in experimentally induced seizures in rats
- CBD post-treatment alleviates rat epileptic-related behaviors
- Pharmacology of cannabinoids in the treatment of epilepsy
- Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection
- Report from a survey of parents regarding the use of cannabidiol in Mexican children with refractory epilepsy
- Protective effects of Cannabidiol against seizures and neuronal death in a rat model of mesial temporal lobe epilepsy
- CBD treatment for refractory seizures in Sturge-Weber Syndrome
- Could cannabidiol be a treatment option for intractable childhood and adolescent epilepsy?
These links are from third-party sites and are provided as a courtesy to the reader.
THE ESSENTIAL GUIDE TO CBD
By the Editors of Reader’s Digest & Project CBD: Everything You Need to Know About What It Helps, Where to Buy It, and How to Take It.