Endocannabinoid System

Endocannabinoid System

Learn about the ECS' role in modulating critical physiological processes.

Endocannabinoid System

child with electrodes on head, awake
The study also provides support for using CBD as a first-line treatment for epilepsy, rather than a last resort.
woman with blue shirt that's holding stomach
Adenomyosis is a menstrual complication that causes heavier bleeding and pain during a woman’s period. About one in five women suffer from it.
Red peppers
Most everyone has bit into a spicy pepper and felt heat permeate their mouth. This feeling comes from activation of TRPV1 receptors.
Advil pills
Ibuprofen distinguishes itself from other NSAIDs because it is also a FAAH inhibitor, it slows the breakdown of anandamide and related molecules.
Apple with measuring tape
Medical Cannabis may include weight loss and reduced risk of obesity-associated medical conditions
crystalized water under a microscope
Scientists from Russia, China, and the USA crystallized the CB2 cannabinoid receptor.
Spices that interact with the endocannabinoid system
The health benefits of many common kitchen spices are mediated by the same cannabinoid receptors in the brain and body that cannabis activates.
Neuroscientist Greg Gerdeman, PhD challenges health professionals and researchers to study cannabis science and therapeutics.
Dr. Ethan Russo discusses clinical endocannabinoid deficiency and ways to target the endocannabinoid system for therapeutic benefit.
Data shows that CBD interacts directly with the CB1 cannabinoid receptor in therapeutically relevant ways while modulating THC's psychoactive effects.

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News & Reports

Top Conditions

In compiling a list of conditions that CBD may help, we examined hundreds of peer-reviewed articles in scientific journals.

Cannabis Conversations

Project CBD talks with Dr. Bonni Goldstein about whole plant cannabis remedies, nonintoxicating cannabinoids, and cancer care for children.
Expert cannabis botanist and geneticist Ryan Lee talks to Project CBD about breeding cannabis, THC & CBD content, and how to interpret lab data.
Project CBD speaks with Dr. Rachel Knox about "endocannabinology," THC/CBD synergies, and whole food nutrition.

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