Depression
Depression
Depression is a serious condition that can lead to a variety of emotional and physical problems and decrease one’s ability to function. Symptoms include fatigue, anxiety, irritability, restlessness, loss of enjoyment, appetite changes, changes in sleep patterns, and thoughts of suicide.
Ketamine is a dissociative anaesthetic that has shown some promise for treating severe depression.
Quick Hit
The story of one woman’s struggle against a rare, devastating illness made worse by cannabis prohibition.
Testimonial
Some say cannabis helps pull them out of depression, and a few admit that they feel a bit more depressed if they use it. What is the real story of cannabis and depression?
Article
CBD and LSD bind to the same serotonin receptor, which mediates psychedelic altered states but CBD has anti-psychotic properties and doesn't cause hallucinations.
Article
What role does the endocannabinoid system play in sleep? Can cannabis help you sleep better?
Article
Dr. Stacey Kerr discusses the controversial topic of cannabis use during pregnancy and shares her clinical experience with expecting mothers.
Article
Linda A. Parker explains the mood enhancing and anti-depressant qualities of CBD and THC.
Book Excerpt
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Science abstracts on CBD and Depression
- Endocannabinoid system dysfunction in mood and related disorders
- Antidepressant-like and anxiolytic-like effects of CBD
- The endocannabinoid system and the treatment of mood and anxiety disorders
- Endocannabinoid signaling in the etiology and treatment of major depressive illness
- Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
- >Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants
- Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa
- Circulating endocannabinoids and N-acyl ethanolamines are differentially regulated in major depression and following exposure to social stress
- Serum contents of endocannabinoids are correlated with blood pressure in depressed women
- The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants
- Antidepressants and changes in concentration of endocannabinoids and n-acylethanolamines in rat brain structures
- Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
- Prohedonic effect of CBD in a rat model of depression
- Antidepressant-like and anxiolytic-like effects of CBD
These links are from third-party sites and are provided as a courtesy to the reader.
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THE ESSENTIAL GUIDE TO CBD
By the Editors of Reader’s Digest & Project CBD: Everything You Need to Know About What It Helps, Where to Buy It, and How to Take It.