An illustration of a woman with some common symptoms of scleroderma. There are two images pulled out to illustrate specific symptoms. The image of a stomach filled with yellow fluid represents esophageal dysfunction. An illustration of a hand represents the occurance of ulcers, calcinosis, sclerodactyly, Raynaud's phenomenon, and telangiectasias.

Scleroderma is an autoimmune disease characterized by the overproduction of collegen and other fibrotic cells. This overproduction generally first appears on the skin, although it can also express systemically.

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