Anandamide

Also known as the ‘bliss molecule’ anandamide is responsible for the feeling of a runner’s high.

In 1993, it made history as the first identified endocannabinoid, or cannabinoid produced within our bodies. It’s identification proved that the endocannabinoid system was responsible for more than just mediating the effects of plant-based cannabinoids like THC.

Synonyms: 
AEA,
N-arachidonoylethanolamine

Summary from Wikipedia:

Anandamide, also known as N-arachidonoylethanolamine (AEA), is a fatty acid neurotransmitter derived from the non-oxidative metabolism of eicosatetraenoic acid (arachidonic acid), an essential omega-6 fatty acid. The name is taken from the Sanskrit word ananda, which means "joy, bliss, delight", and amide. It is synthesized from N-arachidonoyl phosphatidylethanolamine by multiple pathways. It is degraded primarily by the fatty acid amide hydrolase (FAAH) enzyme, which converts anandamide into ethanolamine and arachidonic acid. As such, inhibitors of FAAH lead to elevated anandamide levels and are being pursued for therapeutic use.

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