Throughout history, cannabis has been described as a treatment for hundreds of different conditions. If scientists find it hard to believe cannabis can do so much, they may chalk up the results as just a placebo. But the placebo effect is powerful. It accounts for roughly half of the efficacy of opioids and antidepressants. And, ironically, the placebo effect actually functions in part through the endocannabinoid system.
Adrian Devitt-Lee is Project CBD’s chief science writer and a PhD candidate in applied math at the University College in London. He is the co-author of several articles in peer-reviewed journals, including the Journal of Physiology, F1000Research, SIAM Journal on Applied Mathematics, and Physica A.