Adrian Devitt-Lee

Profile photograph of Adrian Devitt-Lee. He is looking off into the distance, standing in front of a pastoral scene.

Adrian Devitt-Lee is Project CBD’s chief science writer and a PhD candidate in applied math at the University College in London. He is the co-author of several articles in peer-reviewed journals, including the Journal of Physiology, F1000Research, SIAM Journal on Applied Mathematics, and Physica A.

Dosing Pure CBD

CBD is clearly a useful medicine in the treatment of some types of epilepsy, yet patients are faced with dilemmas when they must decide which product to use.

Dosing Pure CBD

Roadsigns pointing in two directions

CBD is clearly a useful medicine in the treatment of some types of epilepsy, yet patients are faced with dilemmas when they must decide which product to use, how to incorporate it with other medications, and how to begin dosing. Isolate CBD products have the advantage of being standardized, although they suffer from numerous limitations. There is plentiful evidence that orally ingesting high doses of pure CBD reduces pediatric seizures.

THC Makes Oxycodone Safer

Many prohibitionist arguments are being flipped on their heads. CBD’s anti-anxiety effects have replaced much of the reefer madness mentality. Rather than causing lung cancer, marijuana appears to have anti-cancer activity, if anything. And in spite of the gateway theory, whereby casual cannabis use supposedly escalates to heroin, we find that cannabis helps to treat pain and reduce opiate use. An animal study out of the Scripps Research Institute reaffirms that THC generally reduces the addictiveness of opioids.

Placebo Genetics

sugar cubes on wooden table

Throughout history, cannabis has been described as a treatment for hundreds of different conditions. If scientists find it hard to believe cannabis can do so much, they may chalk up the results as just a placebo. But the placebo effect is powerful. It accounts for roughly half of the efficacy of opioids and antidepressants. And, ironically, the placebo effect actually functions in part through the endocannabinoid system.

Into the Weeds

cannabis with ladybug

A major benefit of legalization is regulation (at least in theory). Cannabis in a legal market can be held to safety standards such as the absence of dangerous pesticides. While autonomous community-enforced regulation can exist without government intervention, this does not happen at the global scale which the cannabis industry has reached today. So how well are governments doing with their pesticides regulations? Bay area journalist Nate Seltenrich recently dug into this issue.

THC & CBD for Dementia

pensive man with glasses

A pilot study recently demonstrated that cannabis extracts can be safely used to ameliorate symptoms of severe dementia. Swiss researchers at Geneva University Hospitals decided to use cannabinoids to help ten patients with severe dementia. They took a 2:1 extract of CBD and THC, titrating patients up to about 20 mg CBD and 10 mg THC per day. The oil extract was infused into cake to make it more palatable to the seniors, and the dose was split across three meals a day.

FAAH Mutation & Pain Insensitivity

Chillblack woman doing yoga

There are curious cases of people who feel no pain or have extreme resistance to discomfort. These individuals are often studied by researchers who hope to develop better methods of pain management. One such woman was discovered after she recovered from a highly painful wrist surgery using Tylenol alone. As researchers at the University College of London found out, she had a history of this sort of endurance, and it appeared to have been passed on to her son. With her consent, they ran genetic tests, identifying two mutation in genes related to FAAH.

Why Insurance Should Pay for Medical Cannabis

Stethascope and money

As CBD and recreational cannabis have gained considerable momentum, important aspects of medical marijuana are falling by the wayside. The magnified focus on economic incentives and tax revenue has overshadowed the significance of cannabis as medicine. Just as with insulin and other life-saving medications, a hyper-vigilance towards profit leads to price gouging and undermines patients’ access to medicine. To ensure patient access, insurance companies need to cover the medical use of cannabis, as Drs.

Cannabinoid Limits for Driving

police car with flashing light

In 2017, Michigan’s government founded a commission to recommend policy on cannabis and driving, specifically how to set THC limits. Two years later, in March 2019, they released their conclusion: [T]he Commission finds there is no scientifically supported threshold of ∆9-THC bodily content that would be indicative of impaired driving (emphasis added).

Thanks to our sponsors and supporters:

Top Stories