Published in full on NORML.
Non-Psychotropic Cannabinoid “Proven To Be Safe” In Humans
The oral administration of the non-psychotropic cannabis plant constituent cannabidiol (CBD) is safe and well tolerated in humans, according to clinical trial data published online by the journal Current Pharmaceutical Design.
Investigators at Kings College in London assessed the physiological and behavioral effects of CBD and THC versus placebo in 16 healthy volunteers in a randomized, double-blind, crossover trial.
Investigators reported that the oral administration of 10 mg of THC was associated with various physiological and behavioral effects—such as increased heart rate and sedation—whereas the oral administration of 600 mg of CBD was not.